RNA Details
Disease Name
diabetic nephropathy
Tissue
kidney
RNA Symbol
mir-27a
RNA ID
MI0000578
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
NA
Target
PPAR gama
Pathway
NA
PubMed ID
27184517
Title
"MicroRNA-27a Induces Mesangial Cell Injury by Targeting of PPARgama, and its In Vivo Knockdown Prevents Progression of Diabetic Nephropathy"
Year
2016
Function
"Pecific reduction of renal miR-27a decreases renal fibrosis, which may be explained in part by its regulation of PPAR gama."